Prognostic Factors and Clinical Characteristics in Pediatric Sudden Sensorineural Hearing Loss: A Retrospective Analysis

IF 1.7 4区 医学 Q2 OTORHINOLARYNGOLOGY Laryngoscope Investigative Otolaryngology Pub Date : 2025-04-10 DOI:10.1002/lio2.70112
Ranshi Zhao, Maoling Huang, Cheng Zhong
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引用次数: 0

Abstract

Objective

To investigate the clinical characteristics and prognostic factors influencing treatment outcomes in pediatric sudden sensorineural hearing loss (PSSNHL).

Methods

A retrospective analysis was conducted on 63 children (64 ears) diagnosed with PSSNHL from January 2013 to December 2023. All patients received either systemic or intra-tympanic steroid therapy. Data on age, tinnitus presence, audiogram types, and initial hearing thresholds were analyzed using SPSS 25.0. Univariate and multivariate logistic regressions were performed to identify significant prognostic factors.

Results

The mean age was 16 years (interquartile range:14–17 years). Median time from symptom onset to treatment was 7 days (interquartile range: 4–13 days). Tinnitus was present in 85.7% of cases. Post-treatment hearing thresholds improved from 84.52 ± 3.29 dB HL to 64.17 ± 4.48 dB HL (p < 0.001). The overall therapeutic efficacy rate was 48.4%. Multivariate analysis identified time from onset to treatment (OR = 0.923; 95% CI: 0.789–0.997; p < 0.01) and initial hearing threshold (OR = 0.939; 95% CI: 0.869–0.981; p < 0.05) as independent prognostic factors.

Conclusions

Early intervention and lower initial hearing thresholds are associated with a better prognosis in PSSNHL. Prompt treatment significantly improves outcomes, highlighting the importance of early diagnosis and intervention.

Level of Evidence

Level 4.

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儿童突发性感音神经性听力损失的预后因素和临床特征:回顾性分析
目的探讨小儿突发性感音神经性听力损失(PSSNHL)的临床特点及影响治疗结果的预后因素。方法对2013年1月至2023年12月诊断为PSSNHL的63例儿童(64耳)进行回顾性分析。所有患者均接受全身或鼓室内类固醇治疗。年龄、耳鸣情况、听力图类型和初始听力阈值数据使用SPSS 25.0进行分析。进行单因素和多因素logistic回归以确定重要的预后因素。结果患者平均年龄16岁(四分位数差14 ~ 17岁)。从症状出现到治疗的中位时间为7天(四分位数范围:4-13天)。85.7%的病例伴有耳鸣。治疗后的听力阈值从84.52±3.29 dB HL提高到64.17±4.48 dB HL (p < 0.001)。总有效率为48.4%。多因素分析确定发病至治疗时间(OR = 0.923;95% ci: 0.789-0.997;p < 0.01)和初始听力阈值(OR = 0.939;95% ci: 0.869-0.981;P < 0.05)作为独立预后因素。结论早期干预和较低的初始听力阈值与PSSNHL患者较好的预后相关。及时治疗可显著改善预后,突出了早期诊断和干预的重要性。证据等级4级。
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来源期刊
CiteScore
3.00
自引率
0.00%
发文量
245
审稿时长
11 weeks
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