{"title":"Auditory neurophysiological characteristics in unilateral deafness: influence of deafness side.","authors":"Seval Ceylan, Şule Çekiç","doi":"10.1080/00016489.2025.2487641","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>The characteristics of auditory processing and reorganization after unilateral deafness remain unclear.</p><p><strong>Aims/objectives: </strong>This study aimed to examine subcortical and cortical auditory neurophysiological features in young adults with unilateral deafness according to the side of deafness.</p><p><strong>Methods: </strong>Patient group: A total of 27 men (25.93- ± 3.64-year old) with unilateral deafness [15 right-sided and 12 left-sided deafness (L-SD)] were included. Twenty-one adult males (29.90 ± 3.05 years) with normal bilateral hearing were included in the Normal Control group. Neurodiagnostic Auditory Brainstem Responses (ABR) and Cortical Auditory Evoked Potentials (CAEP) tests were performed on all participants. ABR and CAEP results were compared between groups.</p><p><strong>Results: </strong>In the right-sided deafness (R-SD) group, ABR wave V amplitudes (left ear) were higher than the control group, and the III-V interpeak latencies were found to be shorter (<i>p</i> = .007, <i>p</i> = .032, respectively). In the L-SD group: CAEP wave P1N1 and N1P2 amplitudes were higher than in the R-SD group (<i>p</i> = .037, <i>p</i> = .015, respectively).</p><p><strong>Conclusions and significance: </strong>Auditory neurophysiological biomarkers in adults with unilateral deafness differ according to the side of the deafness. The results of this study may provide preliminary information for the development of appropriate rehabilitation methods according to the deafness side after single-sided deafness.</p>","PeriodicalId":6880,"journal":{"name":"Acta Oto-Laryngologica","volume":" ","pages":"483-490"},"PeriodicalIF":1.0000,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Acta Oto-Laryngologica","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1080/00016489.2025.2487641","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/4/9 0:00:00","PubModel":"Epub","JCR":"Q3","JCRName":"OTORHINOLARYNGOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
Background: The characteristics of auditory processing and reorganization after unilateral deafness remain unclear.
Aims/objectives: This study aimed to examine subcortical and cortical auditory neurophysiological features in young adults with unilateral deafness according to the side of deafness.
Methods: Patient group: A total of 27 men (25.93- ± 3.64-year old) with unilateral deafness [15 right-sided and 12 left-sided deafness (L-SD)] were included. Twenty-one adult males (29.90 ± 3.05 years) with normal bilateral hearing were included in the Normal Control group. Neurodiagnostic Auditory Brainstem Responses (ABR) and Cortical Auditory Evoked Potentials (CAEP) tests were performed on all participants. ABR and CAEP results were compared between groups.
Results: In the right-sided deafness (R-SD) group, ABR wave V amplitudes (left ear) were higher than the control group, and the III-V interpeak latencies were found to be shorter (p = .007, p = .032, respectively). In the L-SD group: CAEP wave P1N1 and N1P2 amplitudes were higher than in the R-SD group (p = .037, p = .015, respectively).
Conclusions and significance: Auditory neurophysiological biomarkers in adults with unilateral deafness differ according to the side of the deafness. The results of this study may provide preliminary information for the development of appropriate rehabilitation methods according to the deafness side after single-sided deafness.
背景：单侧耳聋后听觉加工和重组的特点尚不清楚。目的：本研究旨在探讨单侧耳聋青壮年患者的皮层下和皮层听觉神经生理特征。方法：患者组：选取单侧耳聋男性27例（25.93±3.64岁），其中右侧耳聋15例，左侧耳聋12例（L-SD）。正常对照组为双侧听力正常的成年男性21例（29.90±3.05岁）。对所有参与者进行神经诊断性听觉脑干反应（ABR）和皮层听觉诱发电位（CAEP）测试。比较两组间ABR和CAEP结果。结果：右侧耳聋（R-SD）组ABR波V幅值（左耳）高于对照组，III-V峰间潜伏期较短(p =。007, p =。032年,分别)。L-SD组CAEP波P1N1和N1P2幅值高于R-SD组(p =。037, p =。015年,分别)。结论及意义：成人单侧耳聋听神经生理生物标志物因耳聋侧边不同而不同。本研究结果可为单侧耳聋后根据耳聋侧面制定相应的康复方法提供初步信息。
期刊介绍：
Acta Oto-Laryngologica is a truly international journal for translational otolaryngology and head- and neck surgery. The journal presents cutting-edge papers on clinical practice, clinical research and basic sciences. Acta also bridges the gap between clinical and basic research.
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