Developing an autoverification framework for medication orders at UNC Health.

IF 2.3 4区 医学 Q3 PHARMACOLOGY & PHARMACY American Journal of Health-System Pharmacy Pub Date : 2025-11-07 DOI:10.1093/ajhp/zxaf081
Noemie M Kanene, Kayla Waldron, Mary-Haston Vest, Stephen F Eckel
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Abstract

Purpose: Autoverification (AV) is the process in which a medication is automatically verified in the electronic health record (EHR), bypassing a pharmacist's approval. If concerns of safety and efficacy for AV are addressed, broad implementation can allow AV to be a powerful tool within a hospital system to verify high-volume, low-risk medication orders. This study aims to identify parameters for risk stratification of medications and develop a replicable framework model for identifying medications appropriate for AV at UNC Health.

Methods: The modified Delphi methodology was utilized to reach consensus on parameters used in a risk stratification tool for medication orders. This tool was applied retroactively to a sample of medication orders at UNC Health during a 1-month period (October 2023) to determine risk of adverse event for potentially autoverified orders.

Results: Fifty-five criteria met consensus for consideration for use for an AV risk appraisal tool. Results from a consensus meeting for criteria that would be used in the autoverification risk appraisal tool (AVRAT) to flag medication orders as "high-risk for AV" were age, estimated glomerular filtration rate, hemoglobin level, platelet count, body weight, and EHR documentation of continuous renal replacement therapy. Twenty medications were selected for an initial proof-of-concept evaluation of the AVRAT. Using AVRAT criteria, it was determined that a total of 6.89% of all October medication orders at UNC Health posed a low risk of a potential adverse event with AV.

Conclusion: A proof-of-concept study for the utilization of AV was effectively developed. The study results indicated that AV can possibly reduce time for medication order review across a hospital system, with a relatively small number of orders being potentially eligible for AV.

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为北卡罗来纳大学健康中心的药物订单开发一个自动验证框架。
免责声明:为了加快文章的发表,AJHP在接受稿件后将尽快在网上发布。被接受的稿件已经过同行评审和编辑,但在技术格式化和作者校对之前会在网上发布。这些手稿不是记录的最终版本,稍后将被最终文章(按照AJHP风格格式化并由作者校对)所取代。用途:自动验证(AV)是在电子健康记录中自动验证药物的过程,绕过药剂师的批准。如果AV的安全性和有效性问题得到解决,广泛实施可以使AV成为医院系统内验证大批量、低风险药物订单的强大工具。本研究旨在确定药物风险分层的参数,并开发一个可复制的框架模型,以确定适合北卡罗来纳大学健康中心AV的药物。方法:采用改进的德尔菲法,对用药单风险分层工具的参数达成共识。该工具追溯应用于北卡罗来纳大学健康中心1个月期间(2023年10月)的药物订单样本,以确定潜在自动验证订单的不良事件风险。结果:55项标准符合考虑使用AV风险评估工具的共识。将用于自动验证风险评估工具(AVRAT)的标准共识会议的结果是,年龄、估计的肾小球滤过率、血红蛋白水平、血小板计数、体重和持续肾脏替代治疗的电子病历记录将被标记为“AV高风险”的药物订单。选择了20种药物进行AVRAT的初步概念验证评估。使用AVRAT标准,确定UNC Health所有10月份的药物订单中有6.89%具有AV潜在不良事件的低风险。结论:有效开发了AV利用的概念验证研究。研究结果表明,AV可能会减少整个医院系统的药物订单审查时间,相对较少的订单可能符合AV的条件。
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来源期刊
CiteScore
2.90
自引率
18.50%
发文量
341
审稿时长
3-8 weeks
期刊介绍: The American Journal of Health-System Pharmacy (AJHP) is the official publication of the American Society of Health-System Pharmacists (ASHP). It publishes peer-reviewed scientific papers on contemporary drug therapy and pharmacy practice innovations in hospitals and health systems. With a circulation of more than 43,000, AJHP is the most widely recognized and respected clinical pharmacy journal in the world.
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