Teaching Video NeuroImage: String Hallucinations in Parkinson Disease.

IF 8.5 1区 医学 Q1 CLINICAL NEUROLOGY Neurology Pub Date : 2025-05-13 Epub Date: 2025-04-08 DOI:10.1212/WNL.0000000000213611
Jacky Ganguly, Shubhrangshu Banerjee, Purba Basu, Soumava Mukherjee, Nilam Singh, Hrishikesh Kumar
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Abstract

Statement of the clinical problem addressed by the case: String hallucination, a complex multimodal hallucination in patients with advanced Parkinson disease (PD).

Brief description of case presentation: Two older patients with advanced PD and dementia presented with a peculiar type of hallucination, in the form of seeing and feeling threads on the surfaces or coming out from the fingers. They continued manipulating these imaginary threads before putting them aside. Quetiapine was helpful in both cases.

Summary of the key teaching point in the case: Apart from the commonly described passage (a brief hallucination of a person, animal, or object passing sideways, within the periphery of the visual field) and presence (sensation of someone or something being present nearby, in the absence of seeing it) hallucinations, a multimodal (visual and tactile) hallucination can be seen in patients with advanced PD, mostly with dementia. The patients described here did not have any fluctuating cognition or other well-formed visual hallucinations as seen in dementia with Lewy bodies (DLB). An atypical antipsychotic like quetiapine is helpful to control such complex forms of hallucinations.

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神经影像教学视频:帕金森病的串联幻觉。
该病例的临床问题陈述:串幻觉,一种晚期帕金森病患者的复杂多模态幻觉。病例表现简述:两名老年PD伴痴呆患者表现出一种特殊的幻觉,以看到和感觉到手指表面有线或从手指中伸出。他们继续操纵这些想象的线索,然后把它们放在一边。奎硫平对这两种情况都有帮助。本案例教学要点总结:除了通常描述的通道幻觉(在视野的外围,一个人、动物或物体从旁边经过的短暂幻觉)和存在幻觉(在看不到的情况下感觉到附近有人或某物存在),在晚期PD患者中可以看到多模态(视觉和触觉)幻觉,主要是痴呆患者。这里描述的患者没有任何波动的认知或其他形成良好的视觉幻觉,如在路易体痴呆(DLB)中所见。非典型抗精神病药物,如奎硫平,有助于控制这种复杂形式的幻觉。
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来源期刊
Neurology
Neurology 医学-临床神经学
CiteScore
12.20
自引率
4.00%
发文量
1973
审稿时长
2-3 weeks
期刊介绍: Neurology, the official journal of the American Academy of Neurology, aspires to be the premier peer-reviewed journal for clinical neurology research. Its mission is to publish exceptional peer-reviewed original research articles, editorials, and reviews to improve patient care, education, clinical research, and professionalism in neurology. As the leading clinical neurology journal worldwide, Neurology targets physicians specializing in nervous system diseases and conditions. It aims to advance the field by presenting new basic and clinical research that influences neurological practice. The journal is a leading source of cutting-edge, peer-reviewed information for the neurology community worldwide. Editorial content includes Research, Clinical/Scientific Notes, Views, Historical Neurology, NeuroImages, Humanities, Letters, and position papers from the American Academy of Neurology. The online version is considered the definitive version, encompassing all available content. Neurology is indexed in prestigious databases such as MEDLINE/PubMed, Embase, Scopus, Biological Abstracts®, PsycINFO®, Current Contents®, Web of Science®, CrossRef, and Google Scholar.
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