Beyond Multiple-Choice Accuracy: Real-World Challenges of Implementing Large Language Models in Healthcare.

IF 6 Q1 MATHEMATICAL & COMPUTATIONAL BIOLOGY Annual Review of Biomedical Data Science Pub Date : 2025-08-01 Epub Date: 2025-04-08 DOI:10.1146/annurev-biodatasci-103123-094851
Yifan Yang, Qiao Jin, Qingqing Zhu, Zhizheng Wang, Francisco Erramuspe Álvarez, Nicholas Wan, Benjamin Hou, Zhiyong Lu
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Abstract

Large language models (LLMs) have gained significant attention in the medical domain for their human-level capabilities, leading to increased efforts to explore their potential in various healthcare applications. However, despite such a promising future, there are multiple challenges and obstacles that remain for their real-world uses in practical settings. This work discusses key challenges for LLMs in medical applications from four unique aspects: operational vulnerabilities, ethical and social considerations, performance and assessment difficulties, and legal and regulatory compliance. Addressing these challenges is crucial for leveraging LLMs to their full potential and ensuring their responsible integration into healthcare.

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超越多项选择的准确性:在医疗保健中实现大型语言模型的现实挑战。
大型语言模型(llm)因其具有人类级别的功能而在医学领域获得了极大的关注,因此人们加大了探索其在各种医疗保健应用中的潜力的努力。然而,尽管有这样一个充满希望的未来,在实际环境中使用它们仍然存在许多挑战和障碍。这项工作从四个独特的方面讨论了法学硕士在医疗应用中的主要挑战:操作漏洞、道德和社会考虑、绩效和评估困难以及法律和法规遵从性。解决这些挑战对于充分发挥法学硕士的潜力并确保其负责任地融入医疗保健行业至关重要。
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来源期刊
CiteScore
11.10
自引率
1.70%
发文量
0
期刊介绍: The Annual Review of Biomedical Data Science provides comprehensive expert reviews in biomedical data science, focusing on advanced methods to store, retrieve, analyze, and organize biomedical data and knowledge. The scope of the journal encompasses informatics, computational, artificial intelligence (AI), and statistical approaches to biomedical data, including the sub-fields of bioinformatics, computational biology, biomedical informatics, clinical and clinical research informatics, biostatistics, and imaging informatics. The mission of the journal is to identify both emerging and established areas of biomedical data science, and the leaders in these fields.
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