Pharmacological rehabilitation for stroke

IF 33.1 1区医学 Q1 CLINICAL NEUROLOGY Nature Reviews Neurology Pub Date : 2025-04-10 DOI:10.1038/s41582-025-01087-6

Lisa Kiani

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脑卒中的药物康复

新的研究表明，表达小蛋白的中间神经元突触的形成是中风后康复后运动改善的基础，并为中风恢复提供了药物靶点。在脑卒中小鼠模型中，基于任务的康复训练选择性地增强了从小白蛋白中间神经元到脑卒中诱发部位神经元的突触输入，从而导致运动恢复。此外，通过药物增强小白蛋白中间神经元功能也达到了同样的结果。研究结果显示了开发中风康复药物的潜力——这是目前缺乏药物治疗的领域。“研究结果显示了开发中风康复药物的潜力。”

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Nature Reviews Neurology 医学-临床神经学

CiteScore

29.90

自引率

0.80%

发文量

138

审稿时长

6-12 weeks

期刊介绍： Nature Reviews Neurology aims to be the premier source of reviews and commentaries for the scientific and clinical communities we serve. We want to provide an unparalleled service to authors, referees, and readers, and we work hard to maximize the usefulness and impact of each article. The journal publishes Research Highlights, Comments, News & Views, Reviews, Consensus Statements, and Perspectives relevant to researchers and clinicians working in the field of neurology. Our broad scope ensures that the work we publish reaches the widest possible audience. Our articles are authoritative, accessible, and enhanced with clearly understandable figures, tables, and other display items. This page gives more detail about the aims and scope of the journal.

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