[Synthesis and anti-ulcer activity of some new compounds with arylthiomethyl-pyridine structure].

Il Farmaco; edizione scientifica Pub Date : 1988-11-01
S Evangelista, M Ghelardoni, A Meli, V Pestellini, G Viti
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Abstract

We report the results of the antiulcer activity of some arylthiomethylpyridine compounds. Some of these showed gastroprotective activity against 96% ethanol-induced gastric lesions greater than Omeprazole. However they possess antiulcer properties lower than the reference compound against Indomethacin-induced gastric ulcers.

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[一些芳基硫甲基吡啶结构新化合物的合成及其抗溃疡活性]。
我们报告了一些芳基硫甲基吡啶化合物的抗溃疡活性的结果。其中一些药物对96%乙醇性胃病变的胃保护作用强于奥美拉唑。然而,他们具有抗溃疡的性质低于对照化合物对吲哚美辛引起的胃溃疡。
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