Akshay Chauhan MBBS , Nischal Ranganath MD, PhD , John P. Scott MD , Paschalis Vergidis MD , Anja C. Roden MD , Philip J. Spencer MD , Mauricio A. Villavicencio MD , Richard C. Daly MD , Sahar A. Saddoughi MD, PhD
{"title":"Redo bilateral lung transplantation in a previous heart-lung transplant recipient for invasive pulmonary scedosporiosis","authors":"Akshay Chauhan MBBS , Nischal Ranganath MD, PhD , John P. Scott MD , Paschalis Vergidis MD , Anja C. Roden MD , Philip J. Spencer MD , Mauricio A. Villavicencio MD , Richard C. Daly MD , Sahar A. Saddoughi MD, PhD","doi":"10.1016/j.jhlto.2025.100247","DOIUrl":null,"url":null,"abstract":"<div><div>Redo-bilateral lung transplant in previous heart-lung transplant is a rare operation. We describe our surgical and medical management experience with a heart-lung transplant recipient who developed chronic lung allograft dysfunction and invasive <em>Scedosporium</em> apiospermum infection. The patient underwent a redo-bilateral lung transplant followed by a combination of inhaled voriconazole, caspofungin, and olorofim for a prolonged period. We observed no issues with bronchial anastomosis healing, and the patient is doing well on 1-year follow-up. This report outlines a successful management approach to this rare complication of heart-lung transplant recipients.</div></div>","PeriodicalId":100741,"journal":{"name":"JHLT Open","volume":"8 ","pages":"Article 100247"},"PeriodicalIF":0.0000,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"JHLT Open","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2950133425000424","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/4/1 0:00:00","PubModel":"Epub","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Redo-bilateral lung transplant in previous heart-lung transplant is a rare operation. We describe our surgical and medical management experience with a heart-lung transplant recipient who developed chronic lung allograft dysfunction and invasive Scedosporium apiospermum infection. The patient underwent a redo-bilateral lung transplant followed by a combination of inhaled voriconazole, caspofungin, and olorofim for a prolonged period. We observed no issues with bronchial anastomosis healing, and the patient is doing well on 1-year follow-up. This report outlines a successful management approach to this rare complication of heart-lung transplant recipients.
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