Elena Gomis-Vicent , John J.D. Turner , Michael A. Nitsche , Davide Rivolta , Volker Thoma
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引用次数: 0
Abstract
Introduction
Impulsivity has been widely associated to risky decision-making and addictive behaviours. Recent research is investigating transcranial direct current stimulation (tDCS) as a potential tool to improve gambling disorder symptomatology; however, few studies have considered the influence of impulsivity on tDCS effects targeting different brain areas to modulate gambling-related behaviours.
Methods
Two experiments were performed with two-session crossover designs using the same methodology and different samples of low and high impulsive participants (N=64). Multielectrode tDCS montages were designed to target right dorsolateral prefrontal cortex (rDLPFC) and ventromedial prefrontal cortex (vmPFC) during Cambridge gambling task (GCT) performance.
Results
Results showed tDCS effects on CGT in both low and high impulsive individuals, revealing specific findings associated to rDLPFC and vmPFC targets respectively. A potential influence of impulsivity on tDCS effects was suggested by the differences in delay aversion between LI and HI, shown only in real stimulation but not in sham. Low and high impulsive participants showed differences in task performance, especially in the lowest and highest risk conditions.
Conclusion
Future neuromodulation research may benefit from taking into consideration factors including personality traits, such as impulsivity and participants individual differences that may impact the responsiveness to tDCS, as well as from employing neuroimaging techniques to identify the underlaying tDCS effects on specific brain circuits.
期刊介绍：
Addictive Behaviors is an international peer-reviewed journal publishing high quality human research on addictive behaviors and disorders since 1975. The journal accepts submissions of full-length papers and short communications on substance-related addictions such as the abuse of alcohol, drugs and nicotine, and behavioral addictions involving gambling and technology. We primarily publish behavioral and psychosocial research but our articles span the fields of psychology, sociology, psychiatry, epidemiology, social policy, medicine, pharmacology and neuroscience. While theoretical orientations are diverse, the emphasis of the journal is primarily empirical. That is, sound experimental design combined with valid, reliable assessment and evaluation procedures are a requisite for acceptance. However, innovative and empirically oriented case studies that might encourage new lines of inquiry are accepted as well. Studies that clearly contribute to current knowledge of etiology, prevention, social policy or treatment are given priority. Scholarly commentaries on topical issues, systematic reviews, and mini reviews are encouraged. We especially welcome multimedia papers that incorporate video or audio components to better display methodology or findings.
Studies can also be submitted to Addictive Behaviors? companion title, the open access journal Addictive Behaviors Reports, which has a particular interest in ''non-traditional'', innovative and empirically-oriented research such as negative/null data papers, replication studies, case reports on novel treatments, and cross-cultural research.
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