Leveraging Organ-on-Chip Models to Investigate Host–Microbiota Dynamics and Targeted Therapies for Inflammatory Bowel Disease (Adv. Healthcare Mater. 10/2025)

Abstract

Inflammatory Bowel Disease-on-Chip

In article 2402756, Alexander S. Mosig and co-workers outline the use of intestine-on-chip models to study host–microbiota interactions and targeted therapies for inflammatory bowel disease (IBD). These advanced in vitro models can support the discovery of microbiota-based treatments and personalized medicine. The image was created by Christian Becker and conceptualized by Tim Kaden.