Bimodal In Situ Analyzer for Circular RNA in Extracellular Vesicles Combined with Machine Learning for Accurate Gastric Cancer Detection (Adv. Sci. 15/2025)
Yuhang Guo, Shihua Luo, Sinian Liu, Chao Yang, Weifeng Lv, Yuxin Liang, Tingting Ji, Wenbin Li, Chunchen Liu, Xin Li, Lei Zheng, Ye Zhang
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引用次数: 0
Abstract
Accurate Gastric Cancer Detection
In this study a bimodal EV-circRNA analyzer (BEISA) for detecting circular RNA in gastric cancerderived extracellular vesicles (EVs) is developed. BEISA employs RF-HCR to generate dual fluorescent and electrochemical signals in situ. Combined with machine learning, it can effectively differentiate early gastric cancer patients from healthy donors. More details can be found in article number 2409202 by Lei Zheng, Ye Zhang, and co-workers.
期刊介绍:
Advanced Science is a prestigious open access journal that focuses on interdisciplinary research in materials science, physics, chemistry, medical and life sciences, and engineering. The journal aims to promote cutting-edge research by employing a rigorous and impartial review process. It is committed to presenting research articles with the highest quality production standards, ensuring maximum accessibility of top scientific findings. With its vibrant and innovative publication platform, Advanced Science seeks to revolutionize the dissemination and organization of scientific knowledge.