Antimicrobial management of unresectable embolisation agent infection: A case report

IF 1.6 4区 医学 Q3 CLINICAL NEUROLOGY Clinical Neurology and Neurosurgery Pub Date : 2025-06-01 Epub Date: 2025-04-14 DOI:10.1016/j.clineuro.2025.108894
Timothy D. Shaw , Suhani Bansal , Jun Lau , Carly Culbert , Ashraf Abouharb , Ian Rennie , Louise McCorry
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引用次数: 0

Abstract

Liquid embolisation agents represent an uncommon but serious site of intracranial infection. Surgical excision of the infected material is typically required to eradicate infection and outcomes are poor in inoperable cases due to recurrent, treatment-refractory ventriculitis. We present our case in whom retained E. coli-infected embolisation glue was managed with antimicrobial therapy only. Following multiple failed courses of antibiotics, we found an aggressive induction phase (12 weeks intravenous therapy) followed by lifelong suppressive oral therapy resulted in sustained clinical recovery at one year’s follow-up.
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不可切除栓塞剂感染的抗菌管理:1例报告
液体栓塞剂是一种罕见但严重的颅内感染。通常需要手术切除感染物质以根除感染,由于复发性难治性脑室炎而无法手术的病例结果很差。我们提出我们的病例,其中保留大肠杆菌感染的栓塞胶仅用抗菌药物治疗。在多次失败的抗生素治疗后,我们发现一个积极的诱导阶段(12周静脉注射治疗),然后是终身抑制口服治疗,在一年的随访中持续的临床恢复。
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来源期刊
Clinical Neurology and Neurosurgery
Clinical Neurology and Neurosurgery 医学-临床神经学
CiteScore
3.70
自引率
5.30%
发文量
358
审稿时长
46 days
期刊介绍: Clinical Neurology and Neurosurgery is devoted to publishing papers and reports on the clinical aspects of neurology and neurosurgery. It is an international forum for papers of high scientific standard that are of interest to Neurologists and Neurosurgeons world-wide.
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