Distal anastomosis new entry tear in acute type A aortic dissection: A risk factor for distal aortic reoperation

IF 1.9 JTCVS open Pub Date : 2025-04-01 Epub Date: 2025-03-02 DOI:10.1016/j.xjon.2025.02.016
Rana-Armaghan Ahmad BS , Prabhvir Marway MD , Carlos Alberto Campello Jorge MD , Katelyn Monaghan BS , Divyaam Satija BS , Carol Ling MS , Shinichi Fukuhara MD , Himanshu Patel MD , G. Michael Deeb MD , Nicholas Burris MD , Bo Yang MD, PhD
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Abstract

Objective

To identify predictive factors for the occurrence of a distal anastomosis new entry tear (DANE) in patients who underwent hemiarch replacement after acute type A aortic dissection (ATAAD) and examine the association of DANE with distal aortic reoperation.

Methods

Between 1996 and March 2021, 434 patients underwent hemiarch replacement for DeBakey I ATAAD, of whom 327 patients had adequate postoperative imaging. Based on the presence of DANE on postoperative computed tomography angiography, patients were divided into the DANE group (n = 81) and the no-DANE group (n = 246). Primary outcomes were the cumulative incidence of distal aortic reoperation and the risk factors for DANE.

Results

Most perioperative characteristics and outcomes, including age, sex, malperfusion syndromes, aortic diameters, and operative mortality were similar in the 2 groups. Using death as a competing factor, the 10-year cumulative incidence of distal aortic reoperation was higher in the DANE group compared to the no-DANE group (30% vs 12%; P = .0001). The hazard ratio for DANE in distal reoperations was 2.28 (P = .005). A multivariable regression model showed that having an aortic surgeon was protective against DANE compared to having a nonaortic surgeon (odds ratio [OR], 0.29; P = .05) and identified branch dissection (OR, 2.42; P = .002) as a risk factor for the occurrence of DANE. Connective tissue disease and large-bore suture (4-0 vs 5-0) were not associated with DANE.

Conclusions

Optimizing surgical techniques to prevent DANE in ATAAD repair may prevent the need for reoperation on the distal aorta in DeBakey type I ATAAD.
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急性A型主动脉夹层远端吻合新入口撕裂:主动脉远端再手术的危险因素
目的探讨急性a型主动脉夹层(ATAAD)术后行灌血置换术后远端吻合口新入口撕裂(DANE)发生的预测因素,并探讨DANE与主动脉远端再手术的关系。方法1996年至2021年3月期间,434例患者接受了DeBakey I型ATAAD的充血置换,其中327例患者有足够的术后影像学检查。根据术后计算机断层血管造影中是否存在DANE,将患者分为DANE组(n = 81)和无DANE组(n = 246)。主要结局是主动脉远端再手术的累积发生率和DANE的危险因素。结果两组患者围手术期的大部分特征和结局,包括年龄、性别、灌注不良综合征、主动脉直径、手术死亡率等均相似。将死亡作为一个竞争因素,与非DANE组相比,DANE组10年主动脉远端再手术的累计发生率更高(30% vs 12%;p = 0.0001)。远端再手术中DANE的风险比为2.28 (P = 0.005)。多变量回归模型显示,与非主动脉外科医生相比,主动脉外科医生对DANE有保护作用(优势比[OR], 0.29;P = 0.05)和鉴别的分支解剖(OR, 2.42;P = .002)是发生DANE的危险因素。结缔组织疾病和大孔缝合(4-0 vs 5-0)与DANE无关。结论优化ATAAD修复术中预防DANE的手术技术可避免DeBakey I型ATAAD远端主动脉再次手术。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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