Do we still need embryologists?

IF 3.5 2区 医学 Q1 OBSTETRICS & GYNECOLOGY Reproductive biomedicine online Pub Date : 2025-04-01 Epub Date: 2025-04-24 DOI:10.1016/j.rbmo.2024.104790
Giovanni Coticchio , Danilo Cimadomo , Laura Rienzi
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Abstract

IVF has given scientists a unique role, one probably unparalleled in other medical disciplines. This role has become increasingly more impactful due to the introduction of breakthrough laboratory interventions, such as intracytoplasmic sperm injection and cryopreservation. More recently, incessant advances in automation, information technology and artificial intelligence have started to transform diverse biomedical disciplines. In IVF, relevant examples are novel equipment that can automatically perform embryo assessment, patient/sample identification, vitrification and sperm manipulation/selection/analysis. This has questioned the role of the embryologist. However, the introduction of novel technology is not straightforward; it generates numerous challenges. Which manual interventions should be automated and why? Do machines perform better than humans? Does automation involve higher treatment costs? At the same time, certain highly intellectual activities, such as the integration of novel categories of data and their interpretation, formulation of novel key performance indicators, generation of novel educational and training contents and enhancement and collaborative research, remain human prerogatives. Therefore, while it is to be expected that direct human intervention will be partly replaced by automated devices, we can envisage that the embryologist's role will not become extinct, but will evolve in new forms. Ideally, this change should be guided by principles safeguarding the ethics of medicine and human activity.
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我们还需要胚胎学家吗?
试管婴儿给了科学家一个独特的角色,一个在其他医学学科中可能无与伦比的角色。由于引入突破性的实验室干预措施,如胞浆内单精子注射和冷冻保存,这一角色变得越来越有影响力。最近,自动化、信息技术和人工智能的不断进步已经开始改变各种生物医学学科。在体外受精中,相关的例子是可以自动进行胚胎评估、患者/样本鉴定、玻璃化和精子操作/选择/分析的新型设备。这对胚胎学家的作用提出了质疑。然而,引进新技术并不简单;它带来了许多挑战。哪些人工干预应该自动化,为什么?机器的表现比人类好吗?自动化是否涉及更高的治疗费用?与此同时,某些高度智力的活动,例如整合新的数据类别及其解释、拟订新的关键绩效指标、产生新的教育和培训内容以及加强和合作研究,仍然是人类的特权。因此,虽然可以预期直接的人类干预将部分被自动化设备所取代,但我们可以设想胚胎学家的角色不会消失,而是会以新的形式发展。理想情况下,这种改变应该以维护医学伦理和人类活动的原则为指导。
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来源期刊
Reproductive biomedicine online
Reproductive biomedicine online 医学-妇产科学
CiteScore
7.20
自引率
7.50%
发文量
391
审稿时长
50 days
期刊介绍: Reproductive BioMedicine Online covers the formation, growth and differentiation of the human embryo. It is intended to bring to public attention new research on biological and clinical research on human reproduction and the human embryo including relevant studies on animals. It is published by a group of scientists and clinicians working in these fields of study. Its audience comprises researchers, clinicians, practitioners, academics and patients. Context: The period of human embryonic growth covered is between the formation of the primordial germ cells in the fetus until mid-pregnancy. High quality research on lower animals is included if it helps to clarify the human situation. Studies progressing to birth and later are published if they have a direct bearing on events in the earlier stages of pregnancy.
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