Gold Nanoparticles as SERS Substrates for MTT Assays

IF 0.48 Q4 Physics and Astronomy Bulletin of the Russian Academy of Sciences: Physics Pub Date : 2025-04-24 DOI:10.1134/S1062873824709565
V. A. Mushenkov, A. M. Burov, V. I. Kukushkin, E. G. Zavyalova
{"title":"Gold Nanoparticles as SERS Substrates for MTT Assays","authors":"V. A. Mushenkov,&nbsp;A. M. Burov,&nbsp;V. I. Kukushkin,&nbsp;E. G. Zavyalova","doi":"10.1134/S1062873824709565","DOIUrl":null,"url":null,"abstract":"<p>Several versions of gold nanoparticles are proposed for detecting formazan formed by the enzymatic reduction of MTT reagent by <i>E. coli</i> enzymes. It is shown that gold nanostars coated with a micellar stabilizer are the most promising SERS substrates for detecting formazan in biological mixtures, reducing the required titer of bacteria by at least an order of magnitude.</p>","PeriodicalId":504,"journal":{"name":"Bulletin of the Russian Academy of Sciences: Physics","volume":"89 2","pages":"232 - 239"},"PeriodicalIF":0.4800,"publicationDate":"2025-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Bulletin of the Russian Academy of Sciences: Physics","FirstCategoryId":"1085","ListUrlMain":"https://link.springer.com/article/10.1134/S1062873824709565","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"Physics and Astronomy","Score":null,"Total":0}
引用次数: 0

Abstract

Several versions of gold nanoparticles are proposed for detecting formazan formed by the enzymatic reduction of MTT reagent by E. coli enzymes. It is shown that gold nanostars coated with a micellar stabilizer are the most promising SERS substrates for detecting formazan in biological mixtures, reducing the required titer of bacteria by at least an order of magnitude.

Abstract Image

查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
金纳米颗粒作为MTT检测的SERS底物
研究人员提出了几种金纳米粒子,用于检测大肠杆菌酶还原 MTT 试剂所形成的胶氮。结果表明,涂有胶束稳定剂的金纳米星是最有前途的 SERS 底物,可用于检测生物混合物中的蚁臢,将所需的细菌滴度降低至少一个数量级。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 去求助
来源期刊
Bulletin of the Russian Academy of Sciences: Physics
Bulletin of the Russian Academy of Sciences: Physics Physics and Astronomy-Physics and Astronomy (all)
CiteScore
0.90
自引率
0.00%
发文量
251
期刊介绍: Bulletin of the Russian Academy of Sciences: Physics is an international peer reviewed journal published with the participation of the Russian Academy of Sciences. It presents full-text articles (regular,  letters  to  the editor, reviews) with the most recent results in miscellaneous fields of physics and astronomy: nuclear physics, cosmic rays, condensed matter physics, plasma physics, optics and photonics, nanotechnologies, solar and astrophysics, physical applications in material sciences, life sciences, etc. Bulletin of the Russian Academy of Sciences: Physics  focuses on the most relevant multidisciplinary topics in natural sciences, both fundamental and applied. Manuscripts can be submitted in Russian and English languages and are subject to peer review. Accepted articles are usually combined in thematic issues on certain topics according to the journal editorial policy. Authors featured in the journal represent renowned scientific laboratories and institutes from different countries, including large international collaborations. There are globally recognized researchers among the authors: Nobel laureates and recipients of other awards, and members of national academies of sciences and international scientific societies.
期刊最新文献
Radiation Field of a Charged Particle Accelerated in a Diode Gap Propagation of Wave Beams with an Initially Fractal Phase Profile Analyzing Heart Tones to Diagnose Pulmonary Hypertension A 3D Model of the Upper Mantle near the Hawaiian Archipelago Based on Surface-Wave Tomography Data Two-Color Parametric Solitons
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1