Fluoroalkylacylsilanes as Novel Ambiphilic Donor–Acceptor Carbene Precursors

Abstract

Carbenes, as highly reactive intermediates, have emerged as pivotal tools in organic synthesis, catalysis, and materials science due to their versatile reactivity and broad applicability. Among the diverse classes of carbenes, donor–acceptor carbenes (DACs) have attracted significant attention owing to their unique electronic properties and exceptional reaction selectivity. The distinctive reactivity of DACs arises from the synergistic electronic interplay between electron-withdrawing and electron-donating groups attached to the carbene center, enabling a wide array of transformations. These attributes have established DACs as indispensable building blocks for constructing complex molecular architectures and achieving precise control over chemical transformation.