[Influence of pre- and post-operative treatment with saline glucose solution on oral surgery wound healing. Histological study in rats].

M A de Cabrera, T Okamoto, C Cabrera-Peralta
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Abstract

The liquids are essential nutrients to normal organic function. The corporal growing and development, and the tissue neoformation are affected by the hydrosaline unbalanced. In 100 albinus rats submitted to 24 hours of hydroprivation in the pre and post-operative periods was studied the effect of the saline/glucose treatment on the wound healing. With five groups of 20 animals was shaped: GI - Control, and GII.1 - Saline/glucose pre-operative treatment, and GIII.1 - Saline/glucose post-operative treatment, and GII.2 - water pre-operative treatment, and G-III.2 - water post-operative treatment. In 1, 3, 9, 15 and 21 post-exodontic days the histological analyses of wound healing was did. The results show that the saline/glucose treatment to promove amount in the bone tissue and the osteoblastic activity, with better recuperation of the unbalanced hydrosaline effect. The conclusion is that: 1) the saline/glucose solution aid the tissue neoformation and the wound healing; 2) this effect is consistent in the pre and post-operative periods.

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术前、术后糖盐溶液对口腔手术创面愈合的影响。大鼠组织学研究[j]。
这些液体是人体正常机能所必需的营养物质。生理盐水失衡影响着体表生长发育和组织新生。研究了100只白化病大鼠手术前后24小时脱水后生理盐水/葡萄糖处理对伤口愈合的影响。分为5组,每组20只,分别为GI - Control, GII.1 -术前盐水/葡萄糖处理,GIII.1 -术后盐水/葡萄糖处理,GII.2 -术前水处理,G-III。2 .术后水处理。分别于拔牙后1、3、9、15、21天对创面愈合情况进行组织学分析。结果表明,生理盐水/葡萄糖处理能促进骨组织中成骨细胞的数量和活性,具有较好的调节不平衡生理盐水的效果。结论:1)生理盐水/葡萄糖溶液有利于组织新生和创面愈合;2)该效果在术前和术后均一致。
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