[Tooth extraction wound healing after administration of vitamin B6 (pyridoxine). Histological study in rats].

M B de Lucia, C Martinelli
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引用次数: 0

Abstract

Male rats with 250 grs of weight were injected daily with 0.1 ml of B6 vitamin by peritoneal (way paths). The animal were sacrificed at three, seven, 10, 15 and 21 day after the upper incisor extraction. Its hemimaxila were retired and fixed in 10% formalin and after had been embedded in paraffin sections were cut with 6 micrometers pick. The analysis of the sections stained by hematoxylin and eosin when compared with the controls showed that: 1) the blood clot and fibrin net are substituted more rapidly by the granulation tissue; 2) granulation tissue is more plentiful, early and mature; 3) the bone tissue is more plentiful and mature.

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服用维生素B6(吡哆醇)后拔牙伤口愈合。大鼠组织学研究[j]。
体重250 g的雄性大鼠每日经腹腔注射维生素B6 0.1 ml。分别于拔牙后第3、7、10、15、21天处死。取其半腋,用10%福尔马林固定,包埋于石蜡切片后,用6微米镐切开。苏木精和伊红染色切片与对照组比较表明:1)血块和纤维蛋白网被肉芽组织更快地取代;2)肉芽组织较丰富,早成熟;3)骨组织更加丰富和成熟。
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