Experimental deafferentation syndromes.

M Levitt
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引用次数: 7

Abstract

Animal models of dysesthesias have been established, and reveal the following major points. Dysesthesias of peripheral nerve or dorsal root origin have a central neural cause. Chronic dysesthesias of spinal origin have a cause which resides in the brain. The origins of these effects are lesions in the spinothalamic system. The causes of these effects are abnormal functionings among opiate, catecholamine, and purine pathways. Denervation supersensitivity is suggested.

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实验性神经分离综合征。
知觉障碍的动物模型已经建立,揭示了以下几点。周围神经或背根源性感觉障碍有中枢神经病因。脊髓性慢性感觉障碍的病因存在于大脑中。这些影响的起源是脊髓丘脑系统的病变。造成这些影响的原因是阿片、儿茶酚胺和嘌呤通路的功能异常。建议去神经超敏。
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Proceedings of the 2nd International Symposium on Dorsal Root Entry Zone (DREZ) Lesions. Durham, N.C., April 24-26, 1987. Abnormal physiology of the dorsal horn as related to the deafferentation syndrome. Neurochemistry of the dorsal horn. Investigation on cerebrospinal fluid opioids and neurotransmitters related to spinal cord stimulation. Historical development of neural transplantation.
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