Pancreatic phospholipase A2 (PPLA2) during human pregnancy.

M O Pulkkinen, J Eskola, E Niemelä, T Thuren
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Abstract

Pancreatic phospholipase A2 in human serum during pregnancy is within the normal range. In the amniotic fluid, the amount of immunoreactive pancreatic phospholipase A2 increases from 1.3 microgram/l at 16 weeks to 2.9 micrograms/l near term, but does not correlate with PLA2-activity. Meconium-stained amniotic fluid had highly elevated pancreatic, but not kinetic, PLA2. The fetal pancreas and its high PLA2-content may contribute to the progressive increase in uterine activity during human pregnancy.

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胰磷脂酶A2 (PPLA2)在人类妊娠中的作用。
妊娠期人血清胰磷脂酶A2在正常范围内。在羊水中,免疫反应性胰腺磷脂酶A2的量从16周时的1.3微克/升增加到近期的2.9微克/升,但与pla2活性无关。羊粪染色羊水胰增高,但不动态PLA2。胎儿胰腺及其高pla2含量可能有助于人类妊娠期间子宫活动的逐渐增加。
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