Epidemiology of alcohol and hypertension.

L J Beilin
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引用次数: 15

Abstract

An association between alcohol consumption, blood pressure levels and the prevalence of hypertension has been described in close to twenty population studies. The relationship is independent of ethnic group, gender, type of alcohol, cigarette smoking and obesity, but additive to effects of obesity and oral contraceptive use. Several studies show a progressive rise in blood pressure throughout the entire range of alcohol consumption. Reports indicating a threshold for the effect at around 30 g ethanol per day (three standard drinks) may be artefactual due to underreporting of drinking levels. Drinkers consuming an average of 3 or more glasses per day have three to four times the prevalence of "hypertension" compared with teetotallers. A randomized, controlled trial of moderating alcohol consumption in normotensives has confirmed a direct pressor action of alcohol and is supported by studies in hypertensives. These observations have important implications for the prevention and management of essential hypertension in most communities.

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酒精与高血压的流行病学研究
近20项人口研究描述了饮酒、血压水平和高血压患病率之间的联系。这种关系与种族、性别、酒精类型、吸烟和肥胖无关,但与肥胖和使用口服避孕药的影响有关。几项研究表明,在整个饮酒范围内,血压会逐渐升高。报告指出,由于少报饮酒量,每天约30克乙醇(三种标准饮料)的影响阈值可能是人为的。每天平均喝三杯或更多杯的饮酒者患高血压的几率是不喝酒者的三到四倍。一项在血压正常者中减少饮酒的随机对照试验证实了酒精的直接降压作用,并得到高血压研究的支持。这些观察结果对大多数社区原发性高血压的预防和管理具有重要意义。
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