Dopamine receptor agonists: new angularly annulated tricyclic compounds.

Il Farmaco; edizione scientifica Pub Date : 1988-01-01
R Perrone, F Berardi, G Bettoni, V Tortorella
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Abstract

In order to study the influence on dopaminergic activity of the exchange of X in rigid dopamine congeners of structure 1, the synthesis of octahydrobenzo [f] trans-quinoxalines (VII c, d) and trans-hexahydro-4H-naphtho[1,2-b][1,4]thiazines (X c, d), is reported.

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多巴胺受体激动剂:新的角环三环化合物。
为了研究结构1的刚性多巴胺同源物X交换对多巴胺能活性的影响,报道了八氢苯并[f]反式喹诺啉(VII c, d)和反式六氢- 4h -萘[1,2-b][1,4]噻嗪(X c, d)的合成。
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