[Antibiotic properties of cultures of the Streptomyces coelicolor group that suppress the growth of strains of the same species].

T D Mukasheva, M Kh Shigaeva
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Abstract

Antimicrobial spectrum of 45 cultures of the S. coelicolor group with respect to closely related strains and other streptomycete species was studied. The spectrum of 7 cultures was narrow and they inhibited closely related strains and certain streptomycete species. These cultures produced antibiotic substances of bacteriocin-like nature. The bacteriocin-like substances of the cultures differed in sensitivity to temperature and proteolytic enzymes and capacity for dialysis through cellophane membranes. Biosynthesis of the antibiotic substances increased after exposure to UV light.

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[抑制同种菌株生长的彩色链霉菌群培养物的抗生素特性]。
研究了45株coelicolor组培养物对近缘菌株和其他链霉菌的抑菌谱。7种培养物的光谱较窄,抑制了近缘菌株和某些链霉菌种类。这些培养物产生类似细菌素性质的抗生素物质。培养物的细菌素样物质在对温度和蛋白水解酶的敏感性以及通过玻璃纸膜的透析能力方面存在差异。紫外线照射后抗生素物质的生物合成增加。
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[Monoclonal antibodies to the yellow fever virus]. [Interferon and bacterial infections]. [Isolation, structure and biological action of yeast mannans]. [Effect of protoplast formation on the antibiotic activity of the Streptomyces fradiae 165 strain--a producer of tylosin]. [Preclinical toxicological study of the new antibiotic eremomycin. Its acute toxicity for laboratory animals].
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