Streptococcal protein G: a sensitive tool for detection of antibodies to human immunodeficiency virus proteins in Western blot analysis.

L Björck, J Blomberg
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引用次数: 7

Abstract

Protein G is a cell wall protein of group C and G streptococci which binds human IgG antibodies of all four subclasses with high affinity. This property of the molecule was utilized to develop a sensitive Western blot assay to detect antibodies against HIV proteins in patient sera.

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链球菌蛋白G:一种在Western blot分析中检测人类免疫缺陷病毒蛋白抗体的敏感工具。
蛋白G是C群和G群链球菌的细胞壁蛋白,与人IgG抗体具有高亲和力。该分子的这一特性被用于开发一种灵敏的Western blot检测,以检测患者血清中抗HIV蛋白的抗体。
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