Reference values and modelling of lung function development as a transcendent function of age, body height and mass.

P Kristufek, M Brezina, P Ciutti, J Strmen, M Mayer
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Abstract

We present new lung function reference values based on an investigation of 1024 healthy subjects aged 6-81 years. The dependent variables, i.e. VC, FEV1, RV, FRC, TLC, PEF, MEF50 and MEF25 are expressed as transcendent functions of age, body height and mass. A single equation covers the age range from 6 to 81 years and reflects certain phenomena such as growth, maturation, ageing, sex differences and the undermass-overmass effect. This allows a more accurate determination of individualized reference values and normal limits.

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肺功能发展作为年龄、身高和质量的超越函数的参考值和模型。
我们通过对1024名6-81岁健康受试者的调查,提出了新的肺功能参考值。因变量VC、FEV1、RV、FRC、TLC、PEF、MEF50、MEF25表示为年龄、身高、质量的超越函数。一个方程涵盖了6岁到81岁的年龄范围,并反映了某些现象,如生长、成熟、衰老、性别差异和质量不足效应。这样可以更准确地确定个体化参考值和正常限值。
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