[Changes in the activity of serum enzymes and other paraclinical indices in experimental liver damage in calves].

Veterinarno-meditsinski nauki Pub Date : 1987-01-01
N Abrashev, P Georgiev, G Angelov, V Ivanov
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Abstract

Six calves were used to formulate a model of liver injury, following up the activity of the serum enzymes LAP, ALD, AP, GPT, GOT, OKT, and guanase. Studied were also the contents of blood sugar, calcium, phosphorus as well as some indices of the lipid metabolism. It was found that even with the least severe injuries of the liver there was a considerable rise of the OKT, guanase, GOT, GPT, and LAP activity. It is believed that the enzyme changes alone could serve as a specific index to detect the earliest injury of the liver.

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[犊牛实验性肝损伤血清酶活性及其他临床旁指标的变化]。
选取6头犊牛建立肝损伤模型,对血清中LAP、ALD、AP、GPT、GOT、OKT和guanase酶活性进行测定。并对血糖、钙、磷含量及脂质代谢指标进行了研究。结果发现,即使在最轻的肝脏损伤中,OKT、guanase、GOT、GPT和LAP活性也显著升高。认为单独的酶变化可以作为检测肝脏早期损伤的特异性指标。
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