[Drug resistance of bacterial strains isolated from sows with the clinical picture of mastitis-metritis-agalactia].

Veterinarno-meditsinski nauki Pub Date : 1987-01-01
N Korudzhiĭski, G Bozhkova, G V Gŭlŭbinov, I Dzhurova, S Georgiev
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Abstract

The disk method with Ericson and Bauer's solid nutrient media were employed to ascertain the drug resistance of a total of 54 strains of Escherichia coli, 25 strains of Staphylococcus aureus, 11 strains of Streptococcus pyogenes, 7 strains of Corynebacterium pyogenes, 7 strains of Streptococcus uberis, 2 strains of Streptococcus agalactiae, and 1 strain of Streptococcus disgalactiae isolated from utero-cervical exudate and milk samples of sows with clinical symptoms of mastitis-metritis-agalactia (MMA). It was found that gentamycin only suppressed 100 per cent of the strains. So far as the other chemotherapeutic agents were concerned the organisms showed a varying extent of resistance. After determining the sensitivity of the strains to drugs two groups of pigs (from which the strains referred to were isolated) were subject to treatment. All 20 sows of the first group were treated with oxytocin only, while the 446 animals of the second group were treated with gentamycin in combination with oxytocin. It was found that effective therapy in the case of MMA was impossible with the application of preparations on the base of the hind lobe of the pituitary only. It is necessary to use chemotherapeutic means tow which the isolated organisms are susceptible.

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[乳腺炎-子宫炎-无乳母猪分离菌株的耐药性研究]。
采用Ericson和Bauer固体营养培养基纸片法对54株大肠杆菌、25株金黄色葡萄球菌、11株化脓性链球菌、7株化脓性棒状杆菌、7株ubercoccus、2株无乳链球菌、2株无乳链球菌、3株细菌进行了耐药性测定。从有乳腺炎-子宫炎-无乳(MMA)临床症状的母猪的子宫-宫颈渗出液和乳汁样本中分离到1株无乳链球菌。结果发现庆大霉素只能抑制100%的菌株。就其他化疗药物而言,这些生物表现出不同程度的耐药性。在确定菌株对药物的敏感性后,对两组猪(所涉及的菌株是从其中分离出来的)进行治疗。第一组的20头母猪只使用催产素,而第二组的446头母猪使用庆大霉素和催产素联合治疗。发现仅在垂体后叶基底部应用制剂是不可能有效治疗MMA的。有必要采用化学治疗手段,因为分离出的微生物易受影响。
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