{"title":"Radiation synovectomy with 165Dy-FHMA: Lymph node uptake and radiation dosimetry calculations","authors":"M.R. Zalutsky, P.P. Venkatesan, R.J. English, S. Shortkroff, C.B. Sledge, S.J. Adelstein","doi":"10.1016/S0047-0740(86)80008-0","DOIUrl":null,"url":null,"abstract":"<div><p>The lymph node uptake of <sup>165</sup>Dy was measured in 25 patients treated by radiation synovectomy via intra-articular injection of <sup>l65</sup>Dy-ferric hydroxide macroaggregates (FHMA). An average of 0.12% of the injected dose was found in the inguinal lymph nodes 19h post injection. This results in a lymph node of 16.6 rad (166mGy), a dose significantly less than that reported following radiation synovectomy with other radiocolloids. Dosimetry calculations for the intra-articular injection of <sup>165</sup>Dy-FHMA are provided in the appendix.</p></div>","PeriodicalId":75939,"journal":{"name":"International journal of nuclear medicine and biology","volume":"12 6","pages":"Pages 457-465"},"PeriodicalIF":0.0000,"publicationDate":"1986-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0047-0740(86)80008-0","citationCount":"27","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"International journal of nuclear medicine and biology","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0047074086800080","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 27
Abstract
The lymph node uptake of 165Dy was measured in 25 patients treated by radiation synovectomy via intra-articular injection of l65Dy-ferric hydroxide macroaggregates (FHMA). An average of 0.12% of the injected dose was found in the inguinal lymph nodes 19h post injection. This results in a lymph node of 16.6 rad (166mGy), a dose significantly less than that reported following radiation synovectomy with other radiocolloids. Dosimetry calculations for the intra-articular injection of 165Dy-FHMA are provided in the appendix.
通过关节内注射l65dy -氢氧化铁大聚集体(FHMA)，测量25例放射滑膜切除术患者的淋巴结对165Dy的摄取。注射后19h，平均0.12%的注射剂量出现在腹股沟淋巴结。这导致16.6 rad (166mGy)的淋巴结，剂量明显低于其他放射性胶体进行放射滑膜切除术后报告的剂量。165Dy-FHMA关节内注射剂量学计算结果见附录。
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