Food intake and nutritional status after gastrectomy.

Human nutrition. Clinical nutrition Pub Date : 1986-07-01
S Bisballe, S Buus, B Lund, I Hessov
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Abstract

Food intake and nutritional status was studied in 67 patients, who had had a gastrectomy 2-30 years earlier, and in a randomly selected, matched group of healthy persons. The gastrectomized patients weighed less than the control persons (women 56.4 +/- 9.5 vs 61.4 +/- 6.9 kg; P less than 0.05; men 72.4 +/- 12.5 vs 77.7 +/- 9.2 kg; P less than 0.02). Compared to the controls the gastrectomized women had a significantly lower fat-free mass (37.8 +/- 4.1 vs 40.7 +/- 4.3 kg; P less than 0.02), whereas the gastrectomized men had a lower fat mass (17.0 +/- 7.8 vs 21.2 +/- 6.0 kg; P less than 0.01). The serum concentration of alkaline phosphatase was raised and the concentration of calcium, phosphorus and 25-hydroxycholecalciferol reduced in the gastrectomized group. None of these results could be explained from the nutritional study as both the intake of energy and protein and the intake of calcium and vitamin D was about the same in the operated and the healthy controls. The serum concentration of 25-hydroxycholecalciferol was significantly higher in the gastrectomized persons taking supplementary vitamin D (21.9 +/- 12.0 vs 11.7 +/- 6.5 ng/ml). A daily supplement of 10 micrograms of vitamin D secured normal serum values. As the serum level of 25-hydroxycholecalciferol is correlated to the degree of osteomalacia, all gastrectomized patients should have at least 10 micrograms vitamin D as a supplement once a day.

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胃切除术后的食物摄入和营养状况。
研究人员对67名2-30年前进行过胃切除术的患者以及随机选择的匹配健康人群的食物摄入和营养状况进行了研究。胃切除术患者体重低于对照组(女性56.4 +/- 9.5 vs 61.4 +/- 6.9 kg;P < 0.05;男子72.4 +/- 12.5 vs 77.7 +/- 9.2;P < 0.02)。与对照组相比,胃切除术妇女的无脂质量显著降低(37.8 +/- 4.1 vs 40.7 +/- 4.3 kg;P < 0.02),而切除胃的男性脂肪量较低(17.0 +/- 7.8 vs 21.2 +/- 6.0 kg;P < 0.01)。去胃组大鼠血清碱性磷酸酶浓度升高,钙、磷和25-羟基胆骨化醇浓度降低。这些结果都不能从营养研究中得到解释,因为手术组和健康组的能量和蛋白质摄入量以及钙和维生素D的摄入量都是一样的。服用补充维生素D的胃切除术患者血清25-羟基胆骨化醇浓度显著升高(21.9 +/- 12.0 vs 11.7 +/- 6.5 ng/ml)。每天补充10微克维生素D可以保证正常的血清值。由于25-羟基胆骨化醇的血清水平与骨软化的程度相关,所有胃切除术患者每天应补充至少10微克维生素D。
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