Synthesis of the potent mutagen 3,5,8-trimethyl-3H-imidazo[4,5-f]quinoxalin-2-amine.

T Nyhammar, S Grivas
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引用次数: 9

Abstract

The mutagenic title compound (5,8-DiMeIQx) was synthesized by two different routes: from 2-methyl-4,6-dinitroaniline; and from 4-chloro-2-methyl-6-nitroaniline. The latter and more convenient route involved 2,1,3-benzoselenadiazole intermediates.

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强诱变剂3,5,8-三甲基- 3h -咪唑[4,5-f]喹诺沙林-2胺的合成
诱变标题化合物(5,8- dimeiqx)通过两种不同的途径合成:由2-甲基-4,6-二硝基苯胺;4-氯-2-甲基-6-硝基苯胺。后一种更方便的途径涉及2,1,3-苯并硒二唑中间体。
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