Effects of inhaled carbon disulfide on sensory-evoked potentials of Long-Evans rats.

C S Rebert, E Becker
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Abstract

Peripheral nerve conduction time and parameters of potentials evoked from brain by somatosensory, auditory, and visual stimulation were studied as a function of the concentration of carbon disulfide (CS2) chronically inhaled by female Long-Evans rats. Thirty rats were divided into three groups of ten each and exposed to air or 400 or 800 ppm CS2 7 hours per day, 7 days per week, for 11 weeks. Stimuli consisted of tail shock, clicks, tone pips, light flashes, and reversing visual patterns to evoke multisensory potentials. Effects were observed on conduction time in the periphery, in brainstem auditory pathways and in the visual system. The effects on pattern-reversal potentials were greater than those on flash-evoked potentials.

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吸入二硫化碳对龙-埃文斯大鼠感觉诱发电位的影响。
研究了雌性Long-Evans大鼠长期吸入二硫化碳(CS2)浓度对周围神经传导时间和体感、听觉、视觉刺激诱发的脑电位参数的影响。30只大鼠被分成三组,每组10只,每天7小时,每周7天,连续11周暴露在400或800 ppm的空气中。刺激包括尾震、咔哒声、音调尖音、闪光和扭转视觉模式以唤起多感觉电位。观察到外周、脑干听觉通路和视觉系统的传导时间的影响。对模式反转电位的影响大于对闪现诱发电位的影响。
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