Comparative hematological data from animals implanted with a total artificial heart containing different valves.

S D Hughes, M D Butler, D L Holmberg, B Y Chiang, J M Grevelink, C Crump, G L Burns, P A Dew, D B Olsen, W J Kolff
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Abstract

A review of animals receiving a TAH with 4 mechanical valves suggests that the least damage to the blood cell components is associated with the BS valve when compared with the MH valve at similar heart rates. Clinical anemia in varying stages was observed in most animals in this study. However, most calves compensated for the increased rate of hemolysis and none required blood transfusions. The BS valve would appear to combine minimal turbulence and mechanical crushing in a physiological setting.

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植入含有不同瓣膜的全人工心脏的动物的比较血液学数据。
一项对接受带有4个机械瓣膜的TAH的动物的回顾表明,在心率相似的情况下,与MH瓣膜相比,BS瓣膜对血细胞成分的损害最小。在本研究中,大多数动物都观察到不同阶段的临床贫血。然而,大多数小牛补偿了溶血率的增加,没有需要输血。在生理环境下,BS阀似乎结合了最小的湍流和机械破碎。
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