Urinary prostaglandin E2 output increases in cesarean section.

A Reshef, A Danon
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Abstract

The urinary output of prostaglandin E2 (PGE2) during and following Cesarean section (CS) was investigated in 21 patients. Urinary PGE2, probably reflecting renal production of PGE2, increased about two-fold during anesthesia and surgery and persisted for at least one additional hour. PGE2 output also correlated with the dose of oxytocin administered. The possibility that renal perfusion may be compromised during CS and that increased synthesis of prostaglandins (PGs) may serve to protect the kidney against ischemia is suggested.

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剖宫产时尿前列腺素E2分泌增加。
对21例剖宫产患者剖宫产术中及术后尿中前列腺素E2 (PGE2)的变化进行了研究。尿PGE2,可能反映了肾脏PGE2的产生,在麻醉和手术期间增加了大约两倍,并持续至少一个小时。PGE2的输出也与催产素的剂量有关。CS期间肾脏灌注可能受到损害,前列腺素(pg)合成增加可能有助于保护肾脏免受缺血。
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