Analysis of immunoreactive insulins in man in relation to the effects of aging

Keiji Kakita, Sachiko Kakita
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引用次数: 2

Abstract

In order to elucidate the effects of aging on insulin content in human pancreas, the immunoelectrophoretic analysis of insulin was applied. The pancreas of senile humans appears to contain less total immunoreactive insulin, because of the decrement of proinsulin fraction after overnight fasting. The results suggest the involvement of insulin biosynthesis according to the aging process.

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人体内免疫反应性胰岛素与衰老的关系分析
为了阐明衰老对人体胰腺胰岛素含量的影响,采用免疫电泳方法对胰岛素进行了分析。老年人的胰腺似乎含有较少的总免疫反应性胰岛素,因为隔夜禁食后胰岛素原分数的减少。结果提示胰岛素的生物合成与衰老过程有关。
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