[Effect of a combination therapy of cisplatin and local irradiation on a mouse fibrosarcoma].

Strahlentherapie Pub Date : 1985-06-01
F Höglmeier, J Kummermehr, K R Trott
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Abstract

The authors applied the method of regrowth delay in order to investigate the effect of a therapy combination consisting of cis-platinum and irradiation on the fibrosarcoma SSK2 in C3H mice. An independent addition of the effects of both therapy modalities was found. It could be shown especially that no elective radiosensitization of hypoxic tumor cells is caused by cis-platinum.

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[顺铂联合局部照射治疗小鼠纤维肉瘤的疗效]。
为了研究顺铂与辐照联合治疗C3H小鼠SSK2型纤维肉瘤的疗效,作者采用再生延迟的方法。发现了两种治疗方式的独立作用。尤其可以证明,顺铂对缺氧肿瘤细胞没有选择性的放射增敏作用。
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