{"title":"Chromatography of alkylating agents","authors":"L. Fishbein, H.L. Falk","doi":"10.1016/0009-5907(69)80003-7","DOIUrl":null,"url":null,"abstract":"<div><p>We have attempted to stress the major areas of diverse chromatographic procedures for the analyses of a broad spectrum of alkylating agents and related derivatives. Chromatographic analyses have played a singularly important role in the elaboration of compound homogeneity, metabolism, degradation and mode of action of these agents. This aspect is to importance in the light of the anticipated increase in the utility of a variety of alkylating agents, <em>e.g.</em>, chemosterilant aziridines.</p></div>","PeriodicalId":78892,"journal":{"name":"Chromatographic reviews","volume":"11 2","pages":"Pages 101-152"},"PeriodicalIF":0.0000,"publicationDate":"1969-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0009-5907(69)80003-7","citationCount":"4","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Chromatographic reviews","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/0009590769800037","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 4
Abstract
We have attempted to stress the major areas of diverse chromatographic procedures for the analyses of a broad spectrum of alkylating agents and related derivatives. Chromatographic analyses have played a singularly important role in the elaboration of compound homogeneity, metabolism, degradation and mode of action of these agents. This aspect is to importance in the light of the anticipated increase in the utility of a variety of alkylating agents, e.g., chemosterilant aziridines.
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