Chromatography of alkylating agents

L. Fishbein, H.L. Falk
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引用次数: 4

Abstract

We have attempted to stress the major areas of diverse chromatographic procedures for the analyses of a broad spectrum of alkylating agents and related derivatives. Chromatographic analyses have played a singularly important role in the elaboration of compound homogeneity, metabolism, degradation and mode of action of these agents. This aspect is to importance in the light of the anticipated increase in the utility of a variety of alkylating agents, e.g., chemosterilant aziridines.

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烷基化剂色谱法
我们试图强调各种色谱程序的主要领域,用于分析广泛的烷基化剂和相关衍生物。色谱分析在这些试剂的化合物均匀性、代谢、降解和作用方式的阐述中起着非常重要的作用。考虑到各种烷基化剂(如化学灭菌剂氮嘧啶)的预期用途的增加,这方面是非常重要的。
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