{"title":"Ribosomal proteins. XXV. Immunological studies on Escherichia coli ribosomal proteins","authors":"G. Stöffler, H.G. Wittmann","doi":"10.1016/0022-2836(71)90436-0","DOIUrl":null,"url":null,"abstract":"<div><div>Antisera specific for each of the twenty-one 30 s proteins and for 24 50 s ribosomal proteins of <em>Escherichia coli</em> were prepared and used to investigate whether there are any extensive sequence homologies between the different proteins.</div><div>No immunological cross-reactions were detected between any of the proteins, except L7 and L12 which gave complete cross-reaction. We conclude that the proteins investigated differ substantially in their sequences, but that proteins L7 and L12 have considerable structure homology.</div></div>","PeriodicalId":369,"journal":{"name":"Journal of Molecular Biology","volume":"62 2","pages":"Pages 407-408, IN23-IN24, 409"},"PeriodicalIF":4.5000,"publicationDate":"1971-12-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Molecular Biology","FirstCategoryId":"99","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/0022283671904360","RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"BIOCHEMISTRY & MOLECULAR BIOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
Antisera specific for each of the twenty-one 30 s proteins and for 24 50 s ribosomal proteins of Escherichia coli were prepared and used to investigate whether there are any extensive sequence homologies between the different proteins.
No immunological cross-reactions were detected between any of the proteins, except L7 and L12 which gave complete cross-reaction. We conclude that the proteins investigated differ substantially in their sequences, but that proteins L7 and L12 have considerable structure homology.
期刊介绍：
Journal of Molecular Biology (JMB) provides high quality, comprehensive and broad coverage in all areas of molecular biology. The journal publishes original scientific research papers that provide mechanistic and functional insights and report a significant advance to the field. The journal encourages the submission of multidisciplinary studies that use complementary experimental and computational approaches to address challenging biological questions.
Research areas include but are not limited to: Biomolecular interactions, signaling networks, systems biology; Cell cycle, cell growth, cell differentiation; Cell death, autophagy; Cell signaling and regulation; Chemical biology; Computational biology, in combination with experimental studies; DNA replication, repair, and recombination; Development, regenerative biology, mechanistic and functional studies of stem cells; Epigenetics, chromatin structure and function; Gene expression; Membrane processes, cell surface proteins and cell-cell interactions; Methodological advances, both experimental and theoretical, including databases; Microbiology, virology, and interactions with the host or environment; Microbiota mechanistic and functional studies; Nuclear organization; Post-translational modifications, proteomics; Processing and function of biologically important macromolecules and complexes; Molecular basis of disease; RNA processing, structure and functions of non-coding RNAs, transcription; Sorting, spatiotemporal organization, trafficking; Structural biology; Synthetic biology; Translation, protein folding, chaperones, protein degradation and quality control.
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