{"title":"Reversal of rabbit atheromatosis by hyperoxia","authors":"K. Kjeldsen, P. Astrup, J. Wanstrup","doi":"10.1016/S0368-1319(69)80005-0","DOIUrl":null,"url":null,"abstract":"<div><p>Twenty-four rabbits were fed standard rabbit pellets plus 2 % cholesterol. Twelve animals were exposed for 10 weeks to 28 % oxygen (atmospheric air + oxygen) and 12 animals to 21 % oxygen (atmospheric air). The degree of visible aortic atheromatosis and the aortic content of total cholesterol, phospholipids and triglycerides were significantly lower in the hyperoxic rabbits. Microscopic examinations supported the macroscopic findings.</p></div>","PeriodicalId":78351,"journal":{"name":"Journal of atherosclerosis research","volume":"10 2","pages":"Pages 173-178"},"PeriodicalIF":0.0000,"publicationDate":"1969-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0368-1319(69)80005-0","citationCount":"67","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of atherosclerosis research","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0368131969800050","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 67
Abstract
Twenty-four rabbits were fed standard rabbit pellets plus 2 % cholesterol. Twelve animals were exposed for 10 weeks to 28 % oxygen (atmospheric air + oxygen) and 12 animals to 21 % oxygen (atmospheric air). The degree of visible aortic atheromatosis and the aortic content of total cholesterol, phospholipids and triglycerides were significantly lower in the hyperoxic rabbits. Microscopic examinations supported the macroscopic findings.