S. Prusty M.S. , J.N. Bhayana M.D. , N.C. Nayak M.D. , S. Singh M.S. , V.S. Singhal M.S. , S.R. Sharma M.D. , P.P. Goel M.D.
{"title":"Primary Mediastinal Choriocarcinoma","authors":"S. Prusty M.S. , J.N. Bhayana M.D. , N.C. Nayak M.D. , S. Singh M.S. , V.S. Singhal M.S. , S.R. Sharma M.D. , P.P. Goel M.D.","doi":"10.1378/chest.56.6.543","DOIUrl":null,"url":null,"abstract":"<div><p>Primary mediastinal choriocarcinoma is a rare entity and is peculiar only to man. Although rigid criteria such as serial biopsies of the gonads are essential to rule out the possibility of such mediastinal tumor as a metastatic lesion, a review of the literature shows that anterior mediastinum is rarely involved by the metastasis from gonadal tumors. The clinical diagnosis of such a tumor can be made by the presence of the triad of chest pain, cough and gynecomastia in a man in the third decade. The prognosis of such a lesion is uniformly hopeless irrespective of the mode of treatment. A case of primary mediastinal choriocarcinoma in a 22-year-old man has been described. This case brings the total number of cases to 16.</p></div>","PeriodicalId":11305,"journal":{"name":"Diseases of the chest","volume":"56 6","pages":"Pages 543-546"},"PeriodicalIF":0.0000,"publicationDate":"1969-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1378/chest.56.6.543","citationCount":"7","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Diseases of the chest","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0096021715346203","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 7
Abstract
Primary mediastinal choriocarcinoma is a rare entity and is peculiar only to man. Although rigid criteria such as serial biopsies of the gonads are essential to rule out the possibility of such mediastinal tumor as a metastatic lesion, a review of the literature shows that anterior mediastinum is rarely involved by the metastasis from gonadal tumors. The clinical diagnosis of such a tumor can be made by the presence of the triad of chest pain, cough and gynecomastia in a man in the third decade. The prognosis of such a lesion is uniformly hopeless irrespective of the mode of treatment. A case of primary mediastinal choriocarcinoma in a 22-year-old man has been described. This case brings the total number of cases to 16.
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