{"title":"The effects of amphetamine, caffeine and methylphenidate on the locomotor activity of rats in an unfamiliar environment","authors":"A.S. Marriott","doi":"10.1016/0028-3908(68)90059-2","DOIUrl":null,"url":null,"abstract":"<div><p>The effects of amphetamine, methylphenidate and caffeine were investigated on the locomotor activity of rats in a novel Y-maze situation. Parallel studies were made using locomotor wheels. Neither amphetamine nor caffeine increased Y-maze activity at doses which increased locomotor wheel activity. In contrast methylphenidate greatly increased activity in the Y-maze indicating a qualitative difference in the effects of this drug.</p></div>","PeriodicalId":14111,"journal":{"name":"International journal of neuropharmacology","volume":"7 6","pages":"Pages 487-491"},"PeriodicalIF":0.0000,"publicationDate":"1968-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0028-3908(68)90059-2","citationCount":"37","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"International journal of neuropharmacology","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/0028390868900592","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 37
Abstract
The effects of amphetamine, methylphenidate and caffeine were investigated on the locomotor activity of rats in a novel Y-maze situation. Parallel studies were made using locomotor wheels. Neither amphetamine nor caffeine increased Y-maze activity at doses which increased locomotor wheel activity. In contrast methylphenidate greatly increased activity in the Y-maze indicating a qualitative difference in the effects of this drug.