Tumorigenicity of a rabbit lymphoid cell line transformed by human T-cell leukemia virus.

Gan Pub Date : 1984-06-01
I Miyoshi, I Kubonishi, S Yoshimoto, Y Ohtsuki, T Akagi
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Abstract

A rabbit lymphoid cell line transformed by human T-cell leukemia virus (HTLV) was inoculated into the peritoneal cavity of six newborn hamsters treated by antilymphocyte serum. All of them developed lethal tumors two weeks after implantation. The tumor cells were chromosomally of rabbit type, and harbored HTLV and HTLV antigens.

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人t细胞白血病病毒转化兔淋巴样细胞系的致瘤性。
用抗淋巴细胞血清将人t细胞白血病病毒(HTLV)转化的兔淋巴样细胞株接种于6只新生仓鼠腹腔。所有患者在植入两周后都出现了致命的肿瘤。肿瘤细胞为兔型染色体,携带HTLV和HTLV抗原。
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