Clinical pharmacology of senile dementia

M. Fisman
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引用次数: 7

Abstract

  • 1.

    1. The pharmacological approaches to the management of senile dementia are critically reviewed, with emphasis on the vasodilator drugs, drugs with combined vasodilator and cerebral activator effect, neurotransmitters and their precursors, neuropeptides, use of antioxidants, stimulants of protein biosynthesis, antiviral agents, chelating agents and anticoagulants.

  • 2.

    2. The assumptions underlying the use of the above agents and their limitations are discussed as well as the methodological problems encountered in setting up adequate drug trials in patients with senile dementia.

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老年性痴呆的临床药理学
1.1. 本文对老年痴呆的药理学治疗方法进行了综述,重点是血管扩张剂、血管扩张剂和脑激活剂联合作用的药物、神经递质及其前体、神经肽、抗氧化剂的使用、蛋白质生物合成兴奋剂、抗病毒药物、螯合剂和抗凝血剂。讨论了使用上述药物的基本假设及其局限性,以及在老年痴呆症患者中建立适当的药物试验时遇到的方法学问题。
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Introduction Author index Introduction Editorial Board Drug induced dementia
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