The effects of benzodiazepines on short-term memory and information processing.

Z Subhan
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引用次数: 29

Abstract

The effects of flunitrazepam 1 mg, triazolam 0.25 mg, lormetazepam 1 mg and placebo on stages of information processing in a Sternberg memory scanning task were investigated in ten normal volunteers. Overall reaction times for the task were increased 1 h following treatment with triazolam and both 1 h and 10 h following treatment with flunitrazepam. Response latencies were not appreciably altered by lormetazepam or placebo. The effects of flunitrazepam and triazolam were found to be localised in the stimulus encoding and serial comparison stages of the reaction process and not in response-selection organisation.

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苯二氮卓类药物对短期记忆和信息处理的影响。
研究了氟硝西泮1 mg、三唑安定0.25 mg、氯甲西泮1 mg和安慰剂对Sternberg记忆扫描任务中信息加工阶段的影响。用三唑安定治疗后1小时,用氟硝西泮治疗后1小时和10小时,任务的总反应时间都增加了。反应潜伏期在氯甲安定或安慰剂组中没有明显改变。氟硝西泮和三唑安定的作用局限于刺激编码和反应过程的连续比较阶段,而不是反应选择组织。
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