{"title":"[Acute effects of intrathecal capsaicin and substance P on nociceptive thresholds in rats].","authors":"B Dib","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>We have compared the effects of a single intrathecal injection of capsaicin or substance P (SP) on the motor responses to radiant heat and electrical nociceptive stimulations in the Rat. With nociceptive electrical stimulation, an immediate hyperalgesia followed capsaicin injection in all Rats. On the other hand, some Rats displayed hyperalgesia after SP while others showed hypoalgesia. Both capsaicin and SP, induced hypoalgesia to radiant heat in 17 rats. In 5 rats no response was obtained.</p>","PeriodicalId":10622,"journal":{"name":"Comptes rendus des seances de l'Academie des sciences. Serie III, Sciences de la vie","volume":"296 20","pages":"969-74"},"PeriodicalIF":0.0000,"publicationDate":"1983-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Comptes rendus des seances de l'Academie des sciences. Serie III, Sciences de la vie","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
We have compared the effects of a single intrathecal injection of capsaicin or substance P (SP) on the motor responses to radiant heat and electrical nociceptive stimulations in the Rat. With nociceptive electrical stimulation, an immediate hyperalgesia followed capsaicin injection in all Rats. On the other hand, some Rats displayed hyperalgesia after SP while others showed hypoalgesia. Both capsaicin and SP, induced hypoalgesia to radiant heat in 17 rats. In 5 rats no response was obtained.
分享
京公网安备 11010802042870号
京ICP备2023020795号-1
求助内容：
应助结果提醒方式：
扫码关注我们
