Correlation between acetylcholine-evoked electrical activity, effect of cyclic AMP and actual redox state in frog rectus muscle.

A Puppi, P Práger, M Dely
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Abstract

In view of the very high correlation coefficient between actual redox state potential level in the biophase and spike activity--triggered by acetylcholine and influenced by cAMP--in skeletal muscles it seems rather reasonable the conclusion that the redox state potential level influences the cooperative effects not only in the case of acetylcholine but, directly, also the actions of cAMP, since the type of the regulatory influence of actual redox state potential level is non-additive in some cases, though additive in others.

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乙酰胆碱诱发蛙直肌电活动、环AMP作用与实际氧化还原状态的相关性。
鉴于骨骼肌中生物相中实际氧化还原电位水平与由乙酰胆碱触发并受cAMP影响的spike活性之间具有很高的相关系数,因此得出氧化还原电位水平不仅影响乙酰胆碱的协同效应,而且直接影响cAMP的作用这一结论似乎是相当合理的。由于实际氧化还原状态电位水平的调节影响类型在某些情况下是非加性的,尽管在其他情况下是加性的。
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