Nutritional studies on anti alpha-amylase: I) Influence on the growth rate, blood picture and biochemistry and histological parameters in rats.

Acta vitaminologica et enzymologica Pub Date : 1984-01-01
M Maranesi, G Carenini, P Gentili
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Abstract

Anti-alpha-amylase is a protein characterized by an antienzymatic activity in the sense that it prevents hydrolysis of the alpha--1,4 glycoside bond of starch. Such action could be exploited for reducing the caloric value of the diet. We studied the in-vivo effectiveness of large doses of anti-alpha-amylase extracted from white beans (Phaseolus vulgaris). The growth rate of rats was clearly impaired, the blood pictures and biochemistry showed modifications, and the internal organ histology revealed alterations in the liver and kidney.

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抗α -淀粉酶的营养研究:1)对大鼠生长速度、血象及生化组织学参数的影响。
抗-淀粉酶是一种具有抗酶活性的蛋白质,它可以阻止淀粉-1,4糖苷键的水解。这种行为可以用来降低饮食的热值。我们研究了从白豆(Phaseolus vulgaris)中提取的大剂量抗-淀粉酶的体内有效性。大鼠的生长速度明显受损,血液图像和生物化学显示改变,内脏器官组织学显示肝脏和肾脏的改变。
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