[Automated cytodiagnosis from the viewpoint in the clinical cytologist].

Microscopica acta. Supplement Pub Date : 1983-01-01
H J Soost
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Abstract

Automated prescreening means to replace visual prescreening by cytotechnologists by a machine. The aim is to reach a better diagnostic level by eliminating human failure. All machine positives whether true positive or false positives have to be examined visually (by cytotechnologists or cytopathologists). If there are many false positives the system will be highly uneconomic. From a clinical point of view the number of false negatives is crucial. The false negative rate may in no case be higher than that reached by cytotechnologists and medical cytologists, but should, if possible be lower. Yardstick for the validation of prescreening systems can only be the diagnostic level of well kept cytologic laboratories of conventional cytology. Systems which do not meet these requirements don't have the least chance of being applied in routine diagnostic cytology.

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[从临床细胞学家的角度看自动细胞诊断]。
自动预筛选意味着用机器代替细胞技术人员的视觉预筛选。目的是通过消除人为故障来达到更好的诊断水平。所有机器阳性,无论是真阳性还是假阳性,都必须目视检查(由细胞技术专家或细胞病理学家)。如果有很多误报,系统将非常不经济。从临床角度来看,假阴性的数量是至关重要的。假阴性率在任何情况下都不得高于细胞技术专家和医学细胞学家所达到的水平,但应尽可能降低。验证预筛选系统的标准只能是常规细胞学实验室的诊断水平。不符合这些要求的系统在常规细胞学诊断中没有应用的机会。
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The early development of electron lenses and electron microscopy. [Necessity for and construction of cytological data banks]. [Physico-chemical bases for staining in manual and mechanical cytodiagnosis]. [Current major features of clinical cytology]. [Problems of preparatory technics].
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