{"title":"Thermodynamics of hapten-antibody interactions.","authors":"T K Mukkur","doi":"10.3109/10409238409102301","DOIUrl":null,"url":null,"abstract":"<p><p>Two schools of thought are currently prevalent regarding the thermodynamic mechanism(s) of hapten-antibody interaction(s). While one school is a proponent of the hapten-antibody reaction being driven predominantly by enthalpy, the second school rationalizes the mechanism as an enthalpy-entropy compensation, the magnitude of the latter being dependent on the temperature at which hapten-antibody interaction is carried out.</p>","PeriodicalId":75744,"journal":{"name":"CRC critical reviews in biochemistry","volume":"16 2","pages":"133-67"},"PeriodicalIF":0.0000,"publicationDate":"1984-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/10409238409102301","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"CRC critical reviews in biochemistry","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.3109/10409238409102301","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Two schools of thought are currently prevalent regarding the thermodynamic mechanism(s) of hapten-antibody interaction(s). While one school is a proponent of the hapten-antibody reaction being driven predominantly by enthalpy, the second school rationalizes the mechanism as an enthalpy-entropy compensation, the magnitude of the latter being dependent on the temperature at which hapten-antibody interaction is carried out.
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