Retrospective serological studies on dengue epidemics in Osaka and Okinawa.

Biken journal Pub Date : 1983-12-01
M Tadano, Y Okuno, T Fukunaga, K Fukai
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Abstract

In Japan, dengue epidemics were recorded once before the end of World War II (1942-1945) on the Main Islands and several times (1893-1955) on the Okinawa Islands. Blood samples were obtained from residents in Osaka and Okinawa, and their antibodies were examined by neutralization tests against dengue and Japanese encephalitis viruses. Of 60 serum samples each from Osaka and Okinawa, 11 and 15 sera, respectively, showed positive titers against one or more dengue serotypes. These results confirm that the epidemics had been very large. Moreover, the results showed that the epidemics had been due to dengue type 1 virus in Osaka and to dengue type 1 and 2 viruses in Okinawa.

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大阪和冲绳登革热流行的回顾性血清学研究。
在日本,第二次世界大战结束前(1942-1945年)在美因群岛记录了一次登革热疫情,在冲绳群岛记录了几次(1893-1955年)登革热疫情。采集了大阪和冲绳居民的血液样本,并通过对登革热和日本脑炎病毒的中和试验检测了他们的抗体。在大阪和冲绳各60份血清样本中,分别有11份和15份血清对一种或多种登革热血清型呈阳性滴度。这些结果证实,流行病曾经非常大。此外,结果表明,大阪的流行是由1型登革热病毒引起的,冲绳的流行是由1型和2型登革热病毒引起的。
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