[Characterization of a subgenomic viral RNA in the polysomes of cells infected with the Moloney murine sarcoma virus].

R Hamelin, M Quibriac, N Honore, M Longuet, A Tavitian
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Abstract

We have detected a 1.6 kb RNA species in the polysomes of cells infected with the m1 strain of Moloney Murine Sarcoma Virus. This RNA contains the cellular transforming sequences (mos) as well as sequences located at both ends of the viral genome and is devoid of other internal viral sequences. This RNA appears to be spliced and might function as the messenger for the transforming protein of the Moloney Murine Sarcoma Virus.

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[感染Moloney小鼠肉瘤病毒的细胞多体中亚基因组病毒RNA的表征]。
我们在感染Moloney小鼠肉瘤病毒m1株的细胞多体中检测到一个1.6 kb的RNA种。该RNA包含细胞转化序列(mos)以及位于病毒基因组两端的序列,并且缺乏其他内部病毒序列。这种RNA似乎是剪接的,可能是Moloney小鼠肉瘤病毒转化蛋白的信使。
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